THE NUCLEAR LAMINA COUPLES MECHANICAL FORCES TO CELL FATE IN THE PREIMPLANTATION EMBRYO VIA ACTIN ORGANIZATION

The nuclear lamina couples mechanical forces to cell fate in the preimplantation embryo via actin organization

Abstract During preimplantation development, contractile forces generated at the apical cortex segregate cells into inner and outer positions of the embryo, establishing the inner cell mass 30" Double Wall Oven (ICM) and trophectoderm.To which extent these forces influence ICM-trophectoderm fate remains unresolved.Here, we found that the nuclear la

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Policosanols lose their lustre as cholesterol-lowering agents

Multi Grinders Policosanols have been purported by one research group to act as effective agents for LDL-cholesterol (LDL-C) lowering in humans.However data from independent researchers have been contradicting results published by the laboratories originating these claims.The purpose of this commentary is therefore to briefly summarize the policosa

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